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20231222155518.0 |
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231222s2001 xx ||||| 00| ||eng c |
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|a (DE-627)NLM111393922
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|a (NLM)11227815
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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1 |
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|a van der Hoeven, N
|e verfasserin
|4 aut
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|a Estimating the 5-percentile of the species sensitivity distributions without any assumptions about the distribution
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|c 2001
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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|b nc
|2 rdacarrier
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|a Date Completed 29.03.2001
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|a Date Revised 30.09.2020
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|a published: Print
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|a Citation Status MEDLINE
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|a A non-parametric method is described to estimate the hazardous concentration for p% of the species, the HCp, and the confidence limits for this value, the HCp(alpha). For this method, all observed sensitivities are ordered from high to low sensitivity. The HC5 is the k-th observation were k is the largest integer below 0.05 x (n + 1). It is described how the HCp(alpha) can be calculated. A table is presented for easy calculation of several conservative confidence limits for the HC5. For the HC5(0.05), a second table is presented which can be used to interpolate between the conservative estimate of the HC5(0.05) and the next higher observed concentration. The non-parametric HC5 and HC5(0.05) estimation is illustrated with an example of sensitivity data on malathion. For this data set, the log-normal HC5 and HC5(0.05) estimations appear to be conservative compared with the non-parametric estimate. It is stressed that HC5 and HC5(0.05) estimates will often be much more affected by the non-randomness of the species set for which sensitivity data are available than by the choice of the statistical method
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|a Comparative Study
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|a Journal Article
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|a Hazardous Substances
|2 NLM
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|a Insecticides
|2 NLM
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| 650 |
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|a Cadmium Chloride
|2 NLM
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| 650 |
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|a J6K4F9V3BA
|2 NLM
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| 650 |
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|a Malathion
|2 NLM
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| 650 |
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|a U5N7SU872W
|2 NLM
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|i Enthalten in
|t Ecotoxicology (London, England)
|d 1992
|g 10(2001), 1 vom: 01. Feb., Seite 25-34
|w (DE-627)NLM098212214
|x 1573-3017
|7 nnns
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| 773 |
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|g volume:10
|g year:2001
|g number:1
|g day:01
|g month:02
|g pages:25-34
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|a AR
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|d 10
|j 2001
|e 1
|b 01
|c 02
|h 25-34
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