Estimating the 5-percentile of the species sensitivity distributions without any assumptions about the distribution
A non-parametric method is described to estimate the hazardous concentration for p% of the species, the HCp, and the confidence limits for this value, the HCp(alpha). For this method, all observed sensitivities are ordered from high to low sensitivity. The HC5 is the k-th observation were k is the l...
| Veröffentlicht in: | Ecotoxicology (London, England). - 1992. - 10(2001), 1 vom: 01. Feb., Seite 25-34 |
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| 1. Verfasser: | |
| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2001
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| Zugriff auf das übergeordnete Werk: | Ecotoxicology (London, England) |
| Schlagworte: | Comparative Study Journal Article Hazardous Substances Insecticides Cadmium Chloride J6K4F9V3BA Malathion U5N7SU872W |
| Zusammenfassung: | A non-parametric method is described to estimate the hazardous concentration for p% of the species, the HCp, and the confidence limits for this value, the HCp(alpha). For this method, all observed sensitivities are ordered from high to low sensitivity. The HC5 is the k-th observation were k is the largest integer below 0.05 x (n + 1). It is described how the HCp(alpha) can be calculated. A table is presented for easy calculation of several conservative confidence limits for the HC5. For the HC5(0.05), a second table is presented which can be used to interpolate between the conservative estimate of the HC5(0.05) and the next higher observed concentration. The non-parametric HC5 and HC5(0.05) estimation is illustrated with an example of sensitivity data on malathion. For this data set, the log-normal HC5 and HC5(0.05) estimations appear to be conservative compared with the non-parametric estimate. It is stressed that HC5 and HC5(0.05) estimates will often be much more affected by the non-randomness of the species set for which sensitivity data are available than by the choice of the statistical method |
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| Beschreibung: | Date Completed 29.03.2001 Date Revised 30.09.2020 published: Print Citation Status MEDLINE |
| ISSN: | 1573-3017 |