Scale-up of filamentous organisms from tubes and shake-flasks into stirred vessels

The choice of small-scale fermentation systems contributes significantly to a successful scale-up. Creasing of flasks and the chosen shaker parameters influence the production of secondary metabolites in a strain- and even compound-specific manner. Using actinomycetes and fungi as model organisms th...

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Veröffentlicht in:Biochemical engineering journal. - 1998. - 7(2001), 2 vom: 01. März, Seite 127-134
1. Verfasser: Katzer, W (VerfasserIn)
Weitere Verfasser: Blackburn, M, Charman, K, Martin, S, Penn, J, Wrigley, S
Format: Aufsatz
Sprache:English
Veröffentlicht: 2001
Zugriff auf das übergeordnete Werk:Biochemical engineering journal
Schlagworte:Journal Article
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520 |a The choice of small-scale fermentation systems contributes significantly to a successful scale-up. Creasing of flasks and the chosen shaker parameters influence the production of secondary metabolites in a strain- and even compound-specific manner. Using actinomycetes and fungi as model organisms the influence of the small-scale fermentation system on the production of various secondary metabolites is described and the effects on screening success and scale-up are considered 
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700 1 |a Charman, K  |e verfasserin  |4 aut 
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700 1 |a Penn, J  |e verfasserin  |4 aut 
700 1 |a Wrigley, S  |e verfasserin  |4 aut 
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