Scale-up of filamentous organisms from tubes and shake-flasks into stirred vessels
The choice of small-scale fermentation systems contributes significantly to a successful scale-up. Creasing of flasks and the chosen shaker parameters influence the production of secondary metabolites in a strain- and even compound-specific manner. Using actinomycetes and fungi as model organisms th...
| Veröffentlicht in: | Biochemical engineering journal. - 1998. - 7(2001), 2 vom: 01. März, Seite 127-134 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , , , |
| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2001
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| Zugriff auf das übergeordnete Werk: | Biochemical engineering journal |
| Schlagworte: | Journal Article |
| Zusammenfassung: | The choice of small-scale fermentation systems contributes significantly to a successful scale-up. Creasing of flasks and the chosen shaker parameters influence the production of secondary metabolites in a strain- and even compound-specific manner. Using actinomycetes and fungi as model organisms the influence of the small-scale fermentation system on the production of various secondary metabolites is described and the effects on screening success and scale-up are considered |
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| Beschreibung: | Date Revised 30.09.2020 published: Print Citation Status PubMed-not-MEDLINE |
| ISSN: | 1369-703X |