A case of pulmonary metastasis from renal cell carcinoma with complete response to interferon-alpha and tegafur/uracil (UFT) but possibly UFT-induced liver dysfunction and leukoencephalopathy-like symptoms

A 61-year-old man presented with gross hematuria. He underwent left radical nephrectomy under a diagnosis of left renal cell carcinoma without distant metastasis, but bilateral multiple pulmonary metastases appeared 2.5 months after the operation. Though the metastases responded well to combination...

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Détails bibliographiques
Publié dans:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 45(1999), 9 vom: 23. Sept., Seite 621-4
Auteur principal: Suzuki, K (Auteur)
Autres auteurs: Nukui, A, Kobayashi, M, Sugaya, Y, Muraishi, O, Morita, T, Tokue, A
Format: Article
Langue:Japanese
Publié: 1999
Accès à la collection:Hinyokika kiyo. Acta urologica Japonica
Sujets:Case Reports Journal Article Review Interferon-alpha Tegafur 1548R74NSZ Uracil 56HH86ZVCT
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245 1 2 |a A case of pulmonary metastasis from renal cell carcinoma with complete response to interferon-alpha and tegafur/uracil (UFT) but possibly UFT-induced liver dysfunction and leukoencephalopathy-like symptoms 
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520 |a A 61-year-old man presented with gross hematuria. He underwent left radical nephrectomy under a diagnosis of left renal cell carcinoma without distant metastasis, but bilateral multiple pulmonary metastases appeared 2.5 months after the operation. Though the metastases responded well to combination therapy of interferon-alpha and a 1:4 mixture of tegafur and uracil (UFT), the side effects of liver dysfunction and leukoencephalopathy-like symptoms due to UFT appeared 7 months after the beginning of the chemotherapy. These side effects were improved after the cessation of UFT administration 
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