A case of pulmonary metastasis from renal cell carcinoma with complete response to interferon-alpha and tegafur/uracil (UFT) but possibly UFT-induced liver dysfunction and leukoencephalopathy-like symptoms

A 61-year-old man presented with gross hematuria. He underwent left radical nephrectomy under a diagnosis of left renal cell carcinoma without distant metastasis, but bilateral multiple pulmonary metastases appeared 2.5 months after the operation. Though the metastases responded well to combination...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 45(1999), 9 vom: 23. Sept., Seite 621-4
1. Verfasser: Suzuki, K (VerfasserIn)
Weitere Verfasser: Nukui, A, Kobayashi, M, Sugaya, Y, Muraishi, O, Morita, T, Tokue, A
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1999
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:Case Reports Journal Article Review Interferon-alpha Tegafur 1548R74NSZ Uracil 56HH86ZVCT
Beschreibung
Zusammenfassung:A 61-year-old man presented with gross hematuria. He underwent left radical nephrectomy under a diagnosis of left renal cell carcinoma without distant metastasis, but bilateral multiple pulmonary metastases appeared 2.5 months after the operation. Though the metastases responded well to combination therapy of interferon-alpha and a 1:4 mixture of tegafur and uracil (UFT), the side effects of liver dysfunction and leukoencephalopathy-like symptoms due to UFT appeared 7 months after the beginning of the chemotherapy. These side effects were improved after the cessation of UFT administration
Beschreibung:Date Completed 21.12.1999
Date Revised 24.11.2016
published: Print
Citation Status MEDLINE
ISSN:0018-1994