Ectopic expression of B7-1 (CD80) on T lymphocytes in autoimmune lpr and gld mice
Defective Fas-mediated apoptosis in mice, caused by the gld mutation in the fas ligand gene, results in the development of lupus-like autoantibodies and severe lymphoproliferation. We previously demonstrated ectopic expression of the costimulatory molecule B7-1 (CD80) on T lymphocytes in B6/gld mice...
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 91(1999), 3 vom: 01. Juni, Seite 302-9 |
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| Format: | Aufsatz |
| Sprache: | English |
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1999
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
| Schlagworte: | Journal Article Research Support, U.S. Gov't, P.H.S. Antigens, CD Antigens, Differentiation B7-1 Antigen CD28 Antigens CTLA-4 Antigen Ctla4 protein, mouse Fas Ligand Protein Fasl protein, mouse mehr... |