Association among somatic HPRT mutant frequency, peripheral blood T-lymphocyte clonality, and serologic parameters of disease activity in children with juvenile onset dermatomyositis
Somatic mutant frequencies (Mf) were determined using the HPRT T-cell cloning assay of peripheral blood T-lymphocytes from 14 children with juvenile onset dermatomyositis (JDM). Serologic parameters, specifically muscle enzyme determinations in JDM subjects, were correlated with residual lnMf (delta...
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 91(1999), 1 vom: 16. Apr., Seite 61-7 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , |
| Format: | Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
1999
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.) |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Hypoxanthine Phosphoribosyltransferase EC 2.4.2.8 Aspartate Aminotransferases EC 2.6.1.1 Creatine Kinase EC 2.7.3.2 Fructose-Bisphosphate Aldolase |