Tethered bandshift assay and affinity purification of a new DNA-binding protein

DNA-binding proteins can be purified by their affinity for probes with specific sequences that are tethered to magnetic beads. A restriction site at the end of the tether allows release of probe with factor still on it. This probe with bound factor can be bandshifted directly to compare to bandshift...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1991. - 16(1994), 5 vom: 18. Mai, Seite 852-5
1. Verfasser: Ren, L (VerfasserIn)
Weitere Verfasser: Chen, H, Sternberg, E A
Format: Aufsatz
Sprache:English
Veröffentlicht: 1994
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Research Support, Non-U.S. Gov't Technical Report Journal Article DNA-Binding Proteins