A comparison of indoprofen and indomethacin in the treatment of ankylosing spondylitis

A double-blind, crossover trial was carried out to compare the effectiveness and tolerance of indoprofen with indomethacin in the treatment of ankylosing spondylitis. Nineteen patients entered the study and 1 was withdrawn for reasons unrelated to therapy. Patients received 4-weeks' treatment i...

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Veröffentlicht in:Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC). - 1995. - 3(1984), 10 vom: 20., Seite 637-41
1. Verfasser: Armstrong, R D (VerfasserIn)
Weitere Verfasser: Laurent, R, Panayi, G S
Format: Aufsatz
Sprache:English
Veröffentlicht: 1984
Zugriff auf das übergeordnete Werk:Interim guidelines for the control of infections with Vero cytotoxin producing Escherichia coli (VTEC). Subcommittee of the PHLS Working Group on Vero cytotoxin producing Escherichia coli (VTEC)
Schlagworte:Clinical Trial Journal Article Randomized Controlled Trial Phenylpropionates Indoprofen CPE46ZU14N Indomethacin XXE1CET956
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520 |a A double-blind, crossover trial was carried out to compare the effectiveness and tolerance of indoprofen with indomethacin in the treatment of ankylosing spondylitis. Nineteen patients entered the study and 1 was withdrawn for reasons unrelated to therapy. Patients received 4-weeks' treatment in random order, with 200 mg indoprofen 4-times daily and 25 mg indomethacin 4-times daily. Most subjective and objective clinical measurements of disease activity showed a comparable degree of improvement with either drug although few statistically significant changes were observed. There was no statistically significant difference between treatments and, although gastro-intestinal side-effects occurred more commonly with indoprofen, patients known to be intolerant of indomethacin had been excluded from this trial 
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700 1 |a Laurent, R  |e verfasserin  |4 aut 
700 1 |a Panayi, G S  |e verfasserin  |4 aut 
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