A comparison of indoprofen and indomethacin in the treatment of ankylosing spondylitis
A double-blind, crossover trial was carried out to compare the effectiveness and tolerance of indoprofen with indomethacin in the treatment of ankylosing spondylitis. Nineteen patients entered the study and 1 was withdrawn for reasons unrelated to therapy. Patients received 4-weeks' treatment i...
| Publié dans: | Pharmatherapeutica. - 1980. - 3(1984), 10 vom: 13., Seite 637-41 |
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| Auteur principal: | |
| Autres auteurs: | , |
| Format: | Article |
| Langue: | English |
| Publié: |
1984
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| Accès à la collection: | Pharmatherapeutica |
| Sujets: | Clinical Trial Journal Article Randomized Controlled Trial Phenylpropionates Indoprofen CPE46ZU14N Indomethacin XXE1CET956 |
| Résumé: | A double-blind, crossover trial was carried out to compare the effectiveness and tolerance of indoprofen with indomethacin in the treatment of ankylosing spondylitis. Nineteen patients entered the study and 1 was withdrawn for reasons unrelated to therapy. Patients received 4-weeks' treatment in random order, with 200 mg indoprofen 4-times daily and 25 mg indomethacin 4-times daily. Most subjective and objective clinical measurements of disease activity showed a comparable degree of improvement with either drug although few statistically significant changes were observed. There was no statistically significant difference between treatments and, although gastro-intestinal side-effects occurred more commonly with indoprofen, patients known to be intolerant of indomethacin had been excluded from this trial |
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| Description: | Date Completed 20.09.1984 Date Revised 21.11.2013 published: Print Citation Status MEDLINE |
| ISSN: | 0308-051X |