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231221s1988 xx ||||| 00| ||eng c |
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|a pubmed25n0106.xml
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|a (DE-627)NLM031835422
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|a (NLM)3202233
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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100 |
1 |
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|a Kajino, T
|e verfasserin
|4 aut
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245 |
1 |
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|a Trophoblast antigens in human seminal plasma
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1 |
|c 1988
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336 |
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|a Text
|b txt
|2 rdacontent
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337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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338 |
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|a Band
|b nc
|2 rdacarrier
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500 |
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|a Date Completed 17.01.1989
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|a Date Revised 29.10.2019
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|a published: Print
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|a Citation Status MEDLINE
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|a Secondary recurrent spontaneous (2 degrees) aborters manifest persistent IgG, which show differential cytotoxicity patterns with lymphocytes from many donors. These are non-HLA-directed antibodies, which react allotypically with both trophoblast and lymphocytes. The antigens they recognize are designated trophoblast-lymphocyte crossreactive (TLX) antigens. Xenogeneic anti-TLX sera were studied with the use of enzyme-linked-immunosorbent (ELISA) and immunochemical assays to determine the TLX status of seminal plasma. The results showed 1) allotypic TLX antigens are present in seminal plasma; 2) seminal plasma TLX antigens may be membrane associated; 3) by immunoblotting, the molecular weights of antigens reactive with TLX antisera are 15, 22, 28, 33 kD and a smear between 180 and 340 kd; 4) by isoelectric focusing, TLX antigens show pI 4.0, 5.35, 5.9, 6.5, 6.8, and 7.2. Allotypic seminal plasma TLX antigens may provide the antigenic stimuli for persistent maternal humoral immunity
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|a Journal Article
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7 |
|a Autoantigens
|2 NLM
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650 |
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7 |
|a Isoantibodies
|2 NLM
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650 |
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7 |
|a Isoantigens
|2 NLM
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650 |
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7 |
|a trophoblast-lymphocyte cross-reactive antigens
|2 NLM
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700 |
1 |
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|a Torry, D S
|e verfasserin
|4 aut
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700 |
1 |
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|a McIntyre, J A
|e verfasserin
|4 aut
|
700 |
1 |
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|a Faulk, W P
|e verfasserin
|4 aut
|
773 |
0 |
8 |
|i Enthalten in
|t American journal of reproductive immunology and microbiology : AJRIM
|d 1985
|g 17(1988), 3 vom: 23. Juli, Seite 91-5
|w (DE-627)NLM023911689
|x 8755-8920
|7 nnns
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773 |
1 |
8 |
|g volume:17
|g year:1988
|g number:3
|g day:23
|g month:07
|g pages:91-5
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|d 17
|j 1988
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|h 91-5
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