Plasma methotrexate concentrations in urothelial cancer chemotherapy

The plasma methotrexate (MTX) concentration was measured during 50 courses of chemotherapy on 26 urothelial cancer patients. A dose of 300 mg/body MTX was infused within 2 hours and plasma concentrations were measured at the scheduled times. Plasma level at the end of infusion was (2.3 +/- 0.8) x 10...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 36(1990), 9 vom: 14. Sept., Seite 991-6
1. Verfasser: Kitamura, Y (VerfasserIn)
Weitere Verfasser: Watanabe, M, Komatsubara, S, Sakata, Y
Format: Aufsatz
Sprache:Japanese
Veröffentlicht: 1990
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:English Abstract Journal Article Etoposide 6PLQ3CP4P3 Cisplatin Q20Q21Q62J Methotrexate YL5FZ2Y5U1
LEADER 01000naa a22002652 4500
001 NLM022209700
003 DE-627
005 20231221084956.0
007 tu
008 231221s1990 xx ||||| 00| ||jpn c
028 5 2 |a pubmed24n0074.xml 
035 |a (DE-627)NLM022209700 
035 |a (NLM)2239621 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a jpn 
100 1 |a Kitamura, Y  |e verfasserin  |4 aut 
245 1 0 |a Plasma methotrexate concentrations in urothelial cancer chemotherapy 
264 1 |c 1990 
336 |a Text  |b txt  |2 rdacontent 
337 |a ohne Hilfsmittel zu benutzen  |b n  |2 rdamedia 
338 |a Band  |b nc  |2 rdacarrier 
500 |a Date Completed 21.12.1990 
500 |a Date Revised 21.11.2013 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a The plasma methotrexate (MTX) concentration was measured during 50 courses of chemotherapy on 26 urothelial cancer patients. A dose of 300 mg/body MTX was infused within 2 hours and plasma concentrations were measured at the scheduled times. Plasma level at the end of infusion was (2.3 +/- 0.8) x 10(-5) M/L, (2.9 +/- 1.9) x 10(-5) M/L at the 6th-hour, and (1.9 +/- 1.8) x 10(-7) M/L at the 24th-hour after the infusion. The plasma MTX concentration values were inversely correlated with creatinin clearance. In 6 cases of Kock pouch bladder, clean intermittent self catheterization of urine caused no meaningful increase of MTX 
650 4 |a English Abstract 
650 4 |a Journal Article 
650 7 |a Etoposide  |2 NLM 
650 7 |a 6PLQ3CP4P3  |2 NLM 
650 7 |a Cisplatin  |2 NLM 
650 7 |a Q20Q21Q62J  |2 NLM 
650 7 |a Methotrexate  |2 NLM 
650 7 |a YL5FZ2Y5U1  |2 NLM 
700 1 |a Watanabe, M  |e verfasserin  |4 aut 
700 1 |a Komatsubara, S  |e verfasserin  |4 aut 
700 1 |a Sakata, Y  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Hinyokika kiyo. Acta urologica Japonica  |d 1962  |g 36(1990), 9 vom: 14. Sept., Seite 991-6  |w (DE-627)NLM012631779  |x 0018-1994  |7 nnns 
773 1 8 |g volume:36  |g year:1990  |g number:9  |g day:14  |g month:09  |g pages:991-6 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_20 
912 |a GBV_ILN_22 
912 |a GBV_ILN_40 
912 |a GBV_ILN_60 
912 |a GBV_ILN_72 
912 |a GBV_ILN_120 
912 |a GBV_ILN_350 
912 |a GBV_ILN_2001 
912 |a GBV_ILN_2003 
912 |a GBV_ILN_2005 
912 |a GBV_ILN_2006 
912 |a GBV_ILN_2008 
912 |a GBV_ILN_2010 
912 |a GBV_ILN_2012 
912 |a GBV_ILN_2018 
951 |a AR 
952 |d 36  |j 1990  |e 9  |b 14  |c 09  |h 991-6