Clinical evaluation of urinary glycyl-prolyl dipeptidyl aminopeptidase in patients with urological disease
Urinary glycyl-prolyl dipeptidyl aminopeptidase (GP-DAP) activity was measured in 18 healthy adults and 252 patients with urological diseases. The GP-DAP activity was significantly higher in patients with prostatic cancer, bladder cancer or renal cancer and also in patients with acute prostatitis or...
| Veröffentlicht in: | Hinyokika kiyo. Acta urologica Japonica. - 1962. - 36(1990), 12 vom: 29. Dez., Seite 1391-6 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , |
| Format: | Aufsatz |
| Sprache: | Japanese |
| Veröffentlicht: |
1990
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| Zugriff auf das übergeordnete Werk: | Hinyokika kiyo. Acta urologica Japonica |
| Schlagworte: | Journal Article Acetylglucosaminidase EC 3.2.1.52 Aminopeptidases EC 3.4.11.- CD13 Antigens EC 3.4.11.2 Dipeptidyl-Peptidases and Tripeptidyl-Peptidases EC 3.4.14.- Dipeptidyl Peptidase 4 |
| Zusammenfassung: | Urinary glycyl-prolyl dipeptidyl aminopeptidase (GP-DAP) activity was measured in 18 healthy adults and 252 patients with urological diseases. The GP-DAP activity was significantly higher in patients with prostatic cancer, bladder cancer or renal cancer and also in patients with acute prostatitis or pyelonephritis than in healthy adults. GP-DAP activity was also studied during anticancerous chemotherapy and proved to be a sensitive parameter for renal damage as are urinary N-acetyl-beta-D-glucosaminidase, alanine aminopeptidase, beta 2-microglobulin, alpha 1-microglobulin, and albumin. The analysis of tissue activities suggested that GP-DAP was located not only in the renal parenchyma but also in the prostate and seminal vesicles |
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| Beschreibung: | Date Completed 12.04.1991 Date Revised 16.11.2017 published: Print Citation Status MEDLINE |
| ISSN: | 0018-1994 |