Utility of internal markers to improve the accuracy of cystic fibrosis genotype analysis
DNA diagnostic tests often utilize restriction endonuclease digestion of PCR-amplified portions of genes under analysis. When partial digestion occurs, the resulting patterns may lead to error in diagnosis. To overcome such potential errors in cystic fibrosis testing, we have developed internal mark...
| Publié dans: | BioTechniques. - 1991. - 13(1992), 3 vom: 10. Sept., Seite 372-4 |
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| Auteur principal: | |
| Autres auteurs: | , , , , |
| Format: | Article |
| Langue: | English |
| Publié: |
1992
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| Accès à la collection: | BioTechniques |
| Sujets: | Journal Article CFTR protein, human Genetic Markers Membrane Proteins Cystic Fibrosis Transmembrane Conductance Regulator 126880-72-6 |
| Résumé: | DNA diagnostic tests often utilize restriction endonuclease digestion of PCR-amplified portions of genes under analysis. When partial digestion occurs, the resulting patterns may lead to error in diagnosis. To overcome such potential errors in cystic fibrosis testing, we have developed internal markers that can increase the precision and reliability of genotype assignments |
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| Description: | Date Completed 19.11.1992 Date Revised 17.11.2005 published: Print Citation Status MEDLINE |
| ISSN: | 1940-9818 |