Leishmania infantum induces expression of the negative regulatory checkpoint, CTLA‐4, by human naïve CD8+ T cells

Abstract Aims CD8+ T cells are important in mediating protective responses to intracellular pathogens. However, an uncontrolled response may lead to pathology. The role of CD8+ T cells in different clinical manifestations of human leishmaniasis is controversial and poorly understood. We aim to study...

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Bibliographische Detailangaben
Veröffentlicht in:Parasite Immunology. - 41(2019), 9
1. Verfasser: Viana, Agostinho Gonçalves (VerfasserIn)
Weitere Verfasser: Magalhães, Luísa Mourão Dias, Giunchetti, Rodolfo Cordeiro, Dutra, Walderez O., Gollob, Kenneth J.
Format: Online-Aufsatz
Veröffentlicht: 2019
Zugriff auf das übergeordnete Werk:Parasite Immunology
Umfang:6