Dynamics of duplicated gene regulatory networks governing cotton fiber development following polyploidy

© 2025 The Author(s). New Phytologist © 2025 New Phytologist Foundation.

Bibliographische Detailangaben
Veröffentlicht in:The New phytologist. - 1979. - (2025) vom: 08. Okt.
1. Verfasser: Xiong, Xianpeng (VerfasserIn)
Weitere Verfasser: Zhu, De, Duan, Lian, Grover, Corrinne E, Wendel, Jonathan F, Ma, Xiongfeng, Hu, Guanjing
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2025
Zugriff auf das übergeordnete Werk:The New phytologist
Schlagworte:Journal Article GhMYS1 fiber development gene regulatory network (GRN) transcription factors upland cotton
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520 |a Cotton fiber development entails complex genome-wide gene regulatory networks (GRNs) that remain insufficiently resolved. Here, we present integrative analyses of fiber GRNs using public RNA-seq datasets, integrated with genomic, transcriptomic, and cistromic data. We detail the fiber co-expression dynamics and regulatory connections, validating findings with external datasets and transcription factor (TF) binding site data. We elucidate previously uncharacterized TFs that regulate genes involved in fiber-related functions and cellulose synthesis, and identify the regulatory role of two homoeologous G2-like TFs on fiber length. Analysis of duplicated gene expression and network relationships in allopolyploid cotton, which has two co-resident genomes (A, D), revealed novel aspects of asymmetric subgenomic developmental contributions. Whereas D-biased homoeolog pairs drive higher overall gene expression from the D subgenome, TFs from the A subgenome play a preferential regulatory role in the fiber GRN. Following allopolyploid formation, it appears that the trans-regulatory roles of TFs diversified more rapidly between homoeologs than did the cis-regulatory elements of their target genes. Our approach underscores the utility of network analysis for detecting master regulators and provides fresh perspectives on fiber development and polyploid functional genomics through the lens of co-expression and GRN dynamics 
650 4 |a Journal Article 
650 4 |a GhMYS1 
650 4 |a fiber development 
650 4 |a gene regulatory network (GRN) 
650 4 |a transcription factors 
650 4 |a upland cotton 
700 1 |a Zhu, De  |e verfasserin  |4 aut 
700 1 |a Duan, Lian  |e verfasserin  |4 aut 
700 1 |a Grover, Corrinne E  |e verfasserin  |4 aut 
700 1 |a Wendel, Jonathan F  |e verfasserin  |4 aut 
700 1 |a Ma, Xiongfeng  |e verfasserin  |4 aut 
700 1 |a Hu, Guanjing  |e verfasserin  |4 aut 
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