Uncovering the Nanoscopic Phase Behavior of Ternary Solutions in the Presence of Electrolytes : From Pre-Ouzo to Ouzo Regions

In this work, we report a comprehensive study of how electrolyte addition governs the structure and stability of surfactant-free microemulsions in a trans-anethol/ethanol/water system. The universal structural response has been validated, spanning the full range of solution dispersed-phase structuri...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 41(2025), 40 vom: 14. Okt., Seite 27381-27392
Auteur principal: Li, Mingbo (Auteur)
Autres auteurs: Lai, Rushi, Tian, Yadi, Gao, Yawen, Wang, Benlong, Sun, Chao
Format: Article en ligne
Langue:English
Publié: 2025
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
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520 |a In this work, we report a comprehensive study of how electrolyte addition governs the structure and stability of surfactant-free microemulsions in a trans-anethol/ethanol/water system. The universal structural response has been validated, spanning the full range of solution dispersed-phase structurings, from sub-10 nm water-in-oil (W/O) reverse aggregates to oil-in-water (O/W) mesoscopic droplets (∼100 nm) and classical Ouzo droplets (∼1 μm). Experimental results reveal that there is a threshold (∼10-3 M) for electrolyte levels above which O/W nanodroplet coalescence and phase separation are triggered: screening of electrical double layers and "salting-out" of hydrophobic components drive the hydrotrope into fewer, larger droplets. The total oil volume sequestered in the dispersed phase remains essentially constant (∼0.01%), indicating oil redistribution rather than dissolution. In contrast, W/O reverse aggregates (∼3 nm) in a predominantly organic medium display near-complete insensitivity to ionic strength, owing to low dielectric screening and tight interfacial packing that exclude substantial ion uptake. Finally, addition of high salt (e.g., 2.0 M NaCl) to Ouzo droplets accelerates their collapse: large droplets fuse and sediment, leaving only residual nanostructures and confirming electrolyte-driven phase demixing. This insight offers clear guidelines for designing additive-free emulsions with tailored lifetimes and nanostructure architectures across pharmaceutical, food, and materials applications 
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700 1 |a Lai, Rushi  |e verfasserin  |4 aut 
700 1 |a Tian, Yadi  |e verfasserin  |4 aut 
700 1 |a Gao, Yawen  |e verfasserin  |4 aut 
700 1 |a Wang, Benlong  |e verfasserin  |4 aut 
700 1 |a Sun, Chao  |e verfasserin  |4 aut 
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