Virus Enhanced Microrobots for Biofilm Eradication
© 2025 The Author(s). Advanced Materials published by Wiley‐VCH GmbH.
| Publié dans: | Advanced materials (Deerfield Beach, Fla.). - 1998. - (2025) vom: 04. Okt., Seite e08299 |
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| Auteur principal: | |
| Autres auteurs: | , , |
| Format: | Article en ligne |
| Langue: | English |
| Publié: |
2025
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| Accès à la collection: | Advanced materials (Deerfield Beach, Fla.) |
| Sujets: | Journal Article biomedicine infection nanorobots |
| Résumé: | © 2025 The Author(s). Advanced Materials published by Wiley‐VCH GmbH. Biofilms pose significant challenges in biomedical, industrial, and environmental applications due to their inherent resistance to antimicrobial agents. This study introduced an innovative and effective strategy for biofilm eradication by employing virus-conjugated microrobots (virusmicrobots). These biofunctionalized microrobots are synthesized via the hydrothermal method, followed by the functionalization of the viruses. The synergy of microrobots' active movement and the virus's specificity boosted biofilm removal by enabling targeted binding, penetration, and effective delivery into the biofilm matrices. Additionally, compared to microrobots alone, virus@microbots significantly accelerated and refined the process. By integrating biological specificity with magnetic responsiveness, this approach demonstrated the efficacy of virus@microbotsas as a viable antibacterial strategy for biofilm elimination, offering a promising antibacterial platform for combating biofilm-associated infections. Future research should focus on optimizing microrobot design and viral conjugation protocols to enhance scalability and therapeutic specificity, paving the way for clinical translation and broader applications in infection control |
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| Description: | Date Revised 04.10.2025 published: Print-Electronic Citation Status Publisher |
| ISSN: | 1521-4095 |
| DOI: | 10.1002/adma.202508299 |