The State of Single-Cell Atlas Data Visualization in the Biological Literature

Recent advancements have enabled tissue samples to be profiled at the unprecedented level of detail of a single cell. Analysis of these data has enabled discoveries that are relevant to understanding disease and developing therapeutics. Large-scale profiling efforts are underway, which aim to genera...

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Veröffentlicht in:IEEE computer graphics and applications. - 1991. - 45(2025), 5 vom: 01. Sept., Seite 18-34
1. Verfasser: Keller, Mark S (VerfasserIn)
Weitere Verfasser: Morth, Eric, Smits, Thomas C, Warchol, Simon, Guo, Grace, Wang, Qianwen, Krueger, Robert, Pfister, Hanspeter, Gehlenborg, Nils
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2025
Zugriff auf das übergeordnete Werk:IEEE computer graphics and applications
Schlagworte:Journal Article
Beschreibung
Zusammenfassung:Recent advancements have enabled tissue samples to be profiled at the unprecedented level of detail of a single cell. Analysis of these data has enabled discoveries that are relevant to understanding disease and developing therapeutics. Large-scale profiling efforts are underway, which aim to generate "atlas" resources that catalog cellular archetypes, including biomarkers and spatial locations. While the problem of cellular data visualization is not new, the size, resolution, and heterogeneity of single-cell atlas datasets present challenges and opportunities. We survey the usage of visualization to interpret single-cell atlas datasets by assessing over 1800 figure panels from 45 biological publications. We intend for this report to serve as a foundational resource for the visualization community as atlas-scale single-cell datasets are emerging rapidly with aims of advancing our understanding of biological function in health and disease
Beschreibung:Date Completed 29.09.2025
Date Revised 29.09.2025
published: Print
Citation Status MEDLINE
ISSN:1558-1756
DOI:10.1109/MCG.2025.3583979