Surface Crowding Effects in Molecular Recognition by Thrombin Binding Aptamers Conjugated to Gold Nanoparticles
This study addresses the challenge of determining how surface immobilization and crowding affect the binding affinity of DNA/RNA aptamers used in nanoparticle-based biosensors. Binding affinity is a critical determinant of biosensor performance. We employed isothermal titration calorimetry (ITC) to...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 41(2025), 39 vom: 07. Okt., Seite 26730-26737
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| 1. Verfasser: |
Petrek, Zachary
(VerfasserIn) |
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| Weitere Verfasser: |
DeMello, Andrew,
Giagou, Thomas,
Zhang, Yehan,
Dudkin, Robert,
Lwin, Bala,
Chong, Hui Hui,
Ye, Tao |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2025
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Gold
7440-57-5
Aptamers, Nucleotide
Thrombin
EC 3.4.21.5
thrombin aptamer
145563-68-4 |
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