Optimizing Branch Morphology in Gold Nanostars To Improve HER2-Targeted Cytotoxicity in HER2-Overexpressing Cancer Cells in the Presence of Serum Proteins

Gold nanoparticles (AuNPs) have demonstrated significant potential for targeted imaging and drug delivery. However, their effectiveness may be compromised by the nonspecific adsorption of serum proteins, forming a protein corona that traps surface ligands and interferes with receptor targeting. This...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 41(2025), 25 vom: 01. Juli, Seite 15796-15804
1. Verfasser: Malik, Irfan Shafi (VerfasserIn)
Weitere Verfasser: Nair, Nithya K, B, Athira, Mishra, Shambhavi, Unnithan, Shreya, Narayana, Chandrabhas, Bhowmik, Debanjan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2025
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Gold 7440-57-5 Aptamers, Nucleotide ERBB2 protein, human EC 2.7.10.1 Receptor, ErbB-2 Antineoplastic Agents Blood Proteins