Optimizing Branch Morphology in Gold Nanostars To Improve HER2-Targeted Cytotoxicity in HER2-Overexpressing Cancer Cells in the Presence of Serum Proteins

Gold nanoparticles (AuNPs) have demonstrated significant potential for targeted imaging and drug delivery. However, their effectiveness may be compromised by the nonspecific adsorption of serum proteins, forming a protein corona that traps surface ligands and interferes with receptor targeting. This...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 41(2025), 25 vom: 01. Juli, Seite 15796-15804
Auteur principal: Malik, Irfan Shafi (Auteur)
Autres auteurs: Nair, Nithya K, B, Athira, Mishra, Shambhavi, Unnithan, Shreya, Narayana, Chandrabhas, Bhowmik, Debanjan
Format: Article en ligne
Langue:English
Publié: 2025
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Gold 7440-57-5 Aptamers, Nucleotide ERBB2 protein, human EC 2.7.10.1 Receptor, ErbB-2 Antineoplastic Agents Blood Proteins