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20250920232830.0 |
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250716s2025 xx |||||o 00| ||eng c |
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|a 10.1111/vcp.70035
|2 doi
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|a pubmed25n1575.xml
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|a (DE-627)NLM389434280
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|a (NLM)40662223
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Sun, Yuqing
|e verfasserin
|4 aut
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|a Method Comparison and Investigation of Interference Variables of a Hand-Held Hemoglobinometer(HemoCue Hb 201+) in Cats
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|c 2025
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 17.09.2025
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|a Date Revised 20.09.2025
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2025 The Author(s). Veterinary Clinical Pathology published by Wiley Periodicals LLC on behalf of American Society for Veterinary Clinical Pathology.
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|a BACKGROUND: Regular blood sampling to monitor RBC mass in anemic cats can exacerbate anemia. Laboratory-based reporting can delay clinical decisions. A hand-held hemoglobinometer, HemoCue Hb 201+ (HC-201), requires only one drop of blood (10 μL) and provides results within 1 min
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|a OBJECTIVES: This preliminary study aimed to evaluate the utility of HC-201 in cats and investigate the impact of potential interferents on its performance
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|a METHODS: One hundred and fifty-four venous blood samples in EDTA from 93 cats were analyzed. Hemoglobin concentration was measured once using an ADVIA 2120 analyzer and compared to the mean of 2-3 replicate measurements from an HC-201. Agreement and systematic bias between HC-201 and ADVIA results, along with precision between HC-201 replicates, were assessed using Lin's concordance correlation coefficient, non-parametric Bland-Altman, Passing-Bablok regression, and intraclass correlation coefficient. The performance of HC-201 in the presence of anemia, leukocytosis, azotemia, lipemia, icterus, hemolysis, and peripheral versus jugular venipunctures was assessed using Wilcoxon rank-sum tests
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|a RESULTS: Passing-Bablok analysis revealed a significant constant bias (intercept = -2.242, 95% CI: -4.042 to -0.667) but no significant proportional bias (slope = 1.015, 95% CI: 1.000-1.032). HC-201 demonstrated excellent agreement (ρc = 0.989) and precision (ICC = 0.997) with a median bias of -0.67 g/L (p = 0.001). The total observed error was 3.02%, within the allowable limits defined by international standards. Neither anemia, leukocytosis, azotemia, lipemia, nor venipuncture site influenced HC-201 measurements. Samples with icterus and hemolysis were insufficient in number for statistical comparison
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|a CONCLUSIONS: This preliminary study indicates that HC-201 offers reliable point-of-care monitoring for hemoglobin concentration in cats
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|a Journal Article
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|a Comparative Study
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|a ADVIA 2120
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| 650 |
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|a anemia
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| 650 |
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|a blood
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|a feline
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|a hemoglobin
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|a point‐of‐care testing
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| 650 |
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|a Hemoglobins
|2 NLM
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| 700 |
1 |
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|a Yiew, Xiu Ting
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Beeler-Marfisi, Janet
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kerr, Carolyn L
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Monteith, Gabrielle
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Bateman, Shane
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Veterinary clinical pathology
|d 1975
|g 54(2025), 3 vom: 16. Sept., Seite 211-220
|w (DE-627)NLM098159984
|x 1939-165X
|7 nnas
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| 773 |
1 |
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|g volume:54
|g year:2025
|g number:3
|g day:16
|g month:09
|g pages:211-220
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| 856 |
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|u http://dx.doi.org/10.1111/vcp.70035
|3 Volltext
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|d 54
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|h 211-220
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