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|a 10.1016/j.plantsci.2025.112529
|2 doi
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|a eng
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|a Shen, Liting
|e verfasserin
|4 aut
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|a NRDN
|b A novel nuclear degradation tag for targeted protein regulation in Arabidopsis
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|c 2025
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|a Text
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|a Date Completed 12.05.2025
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|a Date Revised 12.05.2025
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Copyright © 2025 Elsevier B.V. All rights reserved.
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|a The regulation of protein levels in plants is essential for improving agricultural productivity. Recent studies have explored inducible degradation systems in plants, with some showing promising advancements. This study introduces the NRDN degradation tag as a novel tool for regulating protein stability within the nucleus in Arabidopsis thaliana. Unlike traditional gene knockout methods, NRDN offers real-time, dynamic control over protein degradation, enabling precise studies of nuclear-localized proteins. This discovery provides a valuable tool for regulating protein stability in specific cellular compartments, which presents a versatile approach for dissecting complex cellular processes and offers broad applications in functional genomics and cellular research
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|a Journal Article
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|a Arabidopsis
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|a Degradation
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|a Nucleus
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|a Peptides
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|a Tag
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|a Arabidopsis Proteins
|2 NLM
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|a Huang, Huizhen
|e verfasserin
|4 aut
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|a Yan, Daqi
|e verfasserin
|4 aut
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|a Ye, Yongsheng
|e verfasserin
|4 aut
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|a Hu, Jun
|e verfasserin
|4 aut
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|i Enthalten in
|t Plant science : an international journal of experimental plant biology
|d 1985
|g 356(2025) vom: 25. Juli, Seite 112529
|w (DE-627)NLM098174193
|x 1873-2259
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|g volume:356
|g year:2025
|g day:25
|g month:07
|g pages:112529
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