A Case of Radical Nephrectomy that Achieved Complete Remission after Combination Therapy with Pembrolizumab and Lenvatinib for Metastatic Renal Cell Carcinoma
An 81-year-old woman to our hospital complaining of backpain and was diagnosed with a left renal tumor with lung and iliac metastasis. A renal tumor biopsy confirmed clear cell renal cell carcinoma. The patient began combination therapy with pembrolizumab and lenvatinib but experienced fatigue and e...
| Veröffentlicht in: | Hinyokika kiyo. Acta urologica Japonica. - 1962. - 71(2025), 3 vom: 13. März, Seite 81-86 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , , , , |
| Format: | Online-Aufsatz |
| Sprache: | Japanese |
| Veröffentlicht: |
2025
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| Zugriff auf das übergeordnete Werk: | Hinyokika kiyo. Acta urologica Japonica |
| Schlagworte: | Journal Article Case Reports English Abstract lenvatinib EE083865G2 Quinolines pembrolizumab DPT0O3T46P Phenylurea Compounds Antibodies, Monoclonal, Humanized |
| Zusammenfassung: | An 81-year-old woman to our hospital complaining of backpain and was diagnosed with a left renal tumor with lung and iliac metastasis. A renal tumor biopsy confirmed clear cell renal cell carcinoma. The patient began combination therapy with pembrolizumab and lenvatinib but experienced fatigue and edema after 1 month. Suspecting cardiac dysfunction induced by Lenvatinib, Lenvatinib was discontinued and treatment with pembrolizumab alone was continued. Three months after treatment initiation, the lung and iliac metastases had resolved, allowing for laparoscopic nephrectomy. Five months post-surgery, no new metastases were detected |
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| Beschreibung: | Date Completed 14.04.2025 Date Revised 14.04.2025 published: Print Citation Status MEDLINE |
| ISSN: | 0018-1994 |
| DOI: | 10.14989/ActaUrolJap_71_3_81 |