Utilizing Functionalized Dual-Microbead Interfaces for Measurements of Amyloid-beta (1-42) with Femtomolar Sensitivity

The presence of amyloid-beta (1-42) in CSF and plasma has been implicated as a pathological hallmark of Alzheimer's disease. Here, we demonstrate a high-sensitivity method of detection and quantification for total Aβ42 utilizing two-antibody functionalized microparticles interfaces. Our method...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 41(2025), 9 vom: 11. März, Seite 5870-5876
1. Verfasser: Pollock, Jennifer M (VerfasserIn)
Weitere Verfasser: Yew, Connor H, Tripathi, Anubhav
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2025
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Amyloid beta-Peptides amyloid beta-protein (1-42) Peptide Fragments Polystyrenes Antibodies, Monoclonal