Binding of cis-[Ru(phen)2(3,4Apy)2]2+ to Model Lipid Membranes : Implications for New Tools in the Development of Antiamyloid Drugs
This study explores the interactions of the cis-[Ru(phen)2(Apy)2]2+ complex (RuApy, phen = 1,10-phenanthroline, Apy = 3,4-aminopyridine) with model lipid membranes to explain the role this complex plays in mitigating Aβ toxicity in PC12 neuronal cells. Fluorescence quenching, surface pressure isothe...
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Bibliographische Detailangaben
Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1999. - 40(2024), 52 vom: 31. Dez., Seite 27345-27355
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1. Verfasser: |
da Cruz Garcia, Maria Laura
(VerfasserIn) |
Weitere Verfasser: |
Paixão, Rafaela Ribeiro,
Pazin, Wallance M,
Oliveira, Osvaldo N Jr,
Cremer, Paul S,
Carlos, Rose Maria |
Format: | Online-Aufsatz
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Sprache: | English |
Veröffentlicht: |
2024
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Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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Schlagworte: | Journal Article
Amyloid beta-Peptides
Organometallic Compounds
Phenanthrolines
Ruthenium
7UI0TKC3U5
Membrane Lipids |