Binding of cis-[Ru(phen)2(3,4Apy)2]2+ to Model Lipid Membranes : Implications for New Tools in the Development of Antiamyloid Drugs

This study explores the interactions of the cis-[Ru(phen)2(Apy)2]2+ complex (RuApy, phen = 1,10-phenanthroline, Apy = 3,4-aminopyridine) with model lipid membranes to explain the role this complex plays in mitigating Aβ toxicity in PC12 neuronal cells. Fluorescence quenching, surface pressure isothe...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1999. - 40(2024), 52 vom: 31. Dez., Seite 27345-27355
1. Verfasser: da Cruz Garcia, Maria Laura (VerfasserIn)
Weitere Verfasser: Paixão, Rafaela Ribeiro, Pazin, Wallance M, Oliveira, Osvaldo N Jr, Cremer, Paul S, Carlos, Rose Maria
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Amyloid beta-Peptides Organometallic Compounds Phenanthrolines Ruthenium 7UI0TKC3U5 Membrane Lipids