Development of a human tyrosinase activity inhibition assay using human melanoma cell lysate

Tyrosinase (TYR) inhibitors are required to treat skin hyperpigmentation. Currently live cell-based TYR assays and mushroom TYR in vitro assays are the common methods used to screen for TYR inhibitors. However, these methods are either time consuming and expensive or are not human TYR (hsTYR) specif...

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Veröffentlicht in:BioTechniques. - 1991. - 76(2024), 11 vom: 28. Nov., Seite 547-551
1. Verfasser: Shi, Gengxuan (VerfasserIn)
Weitere Verfasser: Feng, Yunjiang, Tonissen, Kathryn F
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Human tyrosinase inhibitors arbutin inhibitory assay kojic acid melanoma cell lysate skin pigmentation tyrosinase Monophenol Monooxygenase EC 1.14.18.1 mehr... 6K23F1TT52 Enzyme Inhibitors Pyrones