Structural Elucidation and NMR Spectral Assignments of New Diphenyl Ether Derivatives From Liuweizhiji Gegen-Sangshen Oral Liquid

© 2024 John Wiley & Sons Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Magnetic resonance in chemistry : MRC. - 1985. - 63(2025), 2 vom: 18. Feb., Seite 151-154
1. Verfasser: Cui, Jinghao (VerfasserIn)
Weitere Verfasser: Zhou, Xin, Teng, Baorui, Zhang, Dan, Fu, Xiujuan, Chen, Siwei, Liu, Sijing, Li, Zhi, Lei, Hui
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2025
Zugriff auf das übergeordnete Werk:Magnetic resonance in chemistry : MRC
Schlagworte:Journal Article Liuweizhiji Gegen‐Sangshen oral liquid NMR spectra diphenyl ether derivatives identification structural elucidation Phenyl Ethers Drugs, Chinese Herbal phenyl ether 3O695R5M1U Antineoplastic Agents
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520 |a Chemical investigation of the Liuweizhiji Gegen-Sangshen oral liquid afforded one new diphenyl ether derivative (1), together with one known compound (2). Their structures were established by 1D and 2D NMR, and HR-ESI-MS spectroscopic analysis and the absolute configuration of 1 was confirmed by ECD calculation. Compounds 1 and 2 were evaluated for the cytotoxic activities, and compounds 1 and 2 showed weak cytotoxic activities towards HepG2 human liver cancer cells, with IC50 values of 97.3 and 79.6 μM, respectively 
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700 1 |a Fu, Xiujuan  |e verfasserin  |4 aut 
700 1 |a Chen, Siwei  |e verfasserin  |4 aut 
700 1 |a Liu, Sijing  |e verfasserin  |4 aut 
700 1 |a Li, Zhi  |e verfasserin  |4 aut 
700 1 |a Lei, Hui  |e verfasserin  |4 aut 
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