Fabrication of Engineered Drug-Polymer Composite Particles via Piezoelectric Inkjet Technique for Floating Drug Delivery Systems

This study presents a simple approach for fabricating low-density drug-polymer amorphous solid dispersions (ASDs) using a piezoelectric inkjet method, demonstrating potential applications for floating drug delivery systems (FDDS). By adjusting the ratio of two polymers, polylactic acid, and Eudragit...

Description complète

Détails bibliographiques
Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 40(2024), 48 vom: 03. Dez., Seite 25638-25647
Auteur principal: Kim, Hee Jin (Auteur)
Autres auteurs: Jang, Jiye, Lee, Jieun, Han, Chang Hun, Kim, Jin Woong, Park, Bum Jun
Format: Article en ligne
Langue:English
Publié: 2024
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article poly(lactide) 459TN2L5F5 Polyesters Polymers Drug Carriers
LEADER 01000caa a22002652c 4500
001 NLM38042519X
003 DE-627
005 20250306223602.0
007 cr uuu---uuuuu
008 241118s2024 xx |||||o 00| ||eng c
024 7 |a 10.1021/acs.langmuir.4c03556  |2 doi 
028 5 2 |a pubmed25n1267.xml 
035 |a (DE-627)NLM38042519X 
035 |a (NLM)39556093 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Kim, Hee Jin  |e verfasserin  |4 aut 
245 1 0 |a Fabrication of Engineered Drug-Polymer Composite Particles via Piezoelectric Inkjet Technique for Floating Drug Delivery Systems 
264 1 |c 2024 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 03.12.2024 
500 |a Date Revised 03.12.2024 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a This study presents a simple approach for fabricating low-density drug-polymer amorphous solid dispersions (ASDs) using a piezoelectric inkjet method, demonstrating potential applications for floating drug delivery systems (FDDS). By adjusting the ratio of two polymers, polylactic acid, and Eudragit RLPO, the floatability and drug release rate of the drug-polymer ASD particles can be easily manipulated. Kinetic model analyses have been conducted to interpret the drug release mechanism. This work offers a robust platform for exploring diverse polymer-drug combinations that are applicable to FDDS 
650 4 |a Journal Article 
650 7 |a poly(lactide)  |2 NLM 
650 7 |a 459TN2L5F5  |2 NLM 
650 7 |a Polyesters  |2 NLM 
650 7 |a Polymers  |2 NLM 
650 7 |a Drug Carriers  |2 NLM 
700 1 |a Jang, Jiye  |e verfasserin  |4 aut 
700 1 |a Lee, Jieun  |e verfasserin  |4 aut 
700 1 |a Han, Chang Hun  |e verfasserin  |4 aut 
700 1 |a Kim, Jin Woong  |e verfasserin  |4 aut 
700 1 |a Park, Bum Jun  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Langmuir : the ACS journal of surfaces and colloids  |d 1985  |g 40(2024), 48 vom: 03. Dez., Seite 25638-25647  |w (DE-627)NLM098181009  |x 1520-5827  |7 nnas 
773 1 8 |g volume:40  |g year:2024  |g number:48  |g day:03  |g month:12  |g pages:25638-25647 
856 4 0 |u http://dx.doi.org/10.1021/acs.langmuir.4c03556  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_22 
912 |a GBV_ILN_350 
912 |a GBV_ILN_721 
951 |a AR 
952 |d 40  |j 2024  |e 48  |b 03  |c 12  |h 25638-25647