Integrin Subtypes and Lamellipodia Mediate Spatial Sensing of RGD Ligands during Cell Adhesion
Understanding how the spatial distribution of adhesive ligands regulates cell behavior is crucial for designing biomaterials. This study investigates how precisely controlled ligand spacing affects cell spreading and integrin subtype engagement. Using engineered polyacrylamide hydrogels with gold na...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1999. - 40(2024), 47 vom: 26. Nov., Seite 24882-24891
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| 1. Verfasser: |
Pan, Xiaokai
(VerfasserIn) |
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| Weitere Verfasser: |
Nie, Juan,
Lei, Jiacheng,
Wang, Peng,
Zheng, Kaikai,
Wei, Qiang,
Liu, Xiaojing |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2024
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Oligopeptides
arginyl-glycyl-aspartic acid
78VO7F77PN
Ligands
Gold
7440-57-5
Acrylic Resins
Integrin alpha5beta1
Integrin alphaVbeta3
Hydrogels |
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