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20240930233443.0 |
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240930s2024 xx |||||o 00| ||eng c |
| 024 |
7 |
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|a 10.1111/jfd.14018
|2 doi
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|a pubmed24n1553.xml
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|a (DE-627)NLM378305328
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|a (NLM)39343838
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Krebs, Torben
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Use of cardiac cell cultures from salmonids to measure the cardiotoxic effect of environmental pollutants
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1 |
|c 2024
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Revised 29.09.2024
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|a published: Print-Electronic
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|a Citation Status Publisher
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| 520 |
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|a © 2024 The Author(s). Journal of Fish Diseases published by John Wiley & Sons Ltd.
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|a Environmental stressors such as micro- and nanosized plastic particles (MNPs) or crude oil have a detrimental effect on aquatic animals; however, the impact upon the cardiovascular system of fish remains relatively under-researched. This study presents a novel approach for investigating the effect of crude oil and MNPs on the cardiac system of fish. We used salmonid larvae and cardiac cell cultures derived from hearts of salmonid fish and exposed them to environmental stressors. Following exposure to plastic particles or crude oil, the larvae exhibited some variation in contraction rate. In contrast, significant alterations in the contraction rate were observed in all cardiac cell cultures. The greatest differences between the control and treatment groups were observed in cardiac cell cultures derived from older brown trout. Following 7 days of exposure to MNPs or crude oil in Atlantic salmon larval hearts or cardiac cell cultures, there were only minor responses noted in mRNA expression of the selected marker genes. These findings show the use of a novel in vitro technique contributing to the existing body of knowledge on the impact of MNPs and crude oil on the cardiovascular system of salmonids and the associated risk
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|a Journal Article
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|a cell cultures
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| 650 |
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4 |
|a crude oil
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| 650 |
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4 |
|a heart
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| 650 |
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4 |
|a microplastic
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| 650 |
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4 |
|a nanoplastic
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| 700 |
1 |
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|a Bauer, Julia
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Graff, Sarah
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Teich, Lukas
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Sterneberg, Markus
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Gebert, Marina
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Seibel, Henrike
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Seeger, Bettina
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Steinhagen, Dieter
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Jung-Schroers, Verena
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Adamek, Mikolaj
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Journal of fish diseases
|d 1998
|g (2024) vom: 29. Sept., Seite e14018
|w (DE-627)NLM098166034
|x 1365-2761
|7 nnns
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| 773 |
1 |
8 |
|g year:2024
|g day:29
|g month:09
|g pages:e14018
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| 856 |
4 |
0 |
|u http://dx.doi.org/10.1111/jfd.14018
|3 Volltext
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|a AR
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| 952 |
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|j 2024
|b 29
|c 09
|h e14018
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