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240916s2024 xx |||||o 00| ||eng c |
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|a 10.1021/acs.chemmater.4c01106
|2 doi
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|a eng
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| 100 |
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|a Tirey, Teah N
|e verfasserin
|4 aut
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| 245 |
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|a Nanoscale Surface Chemical Patterning of Soft Polyacrylamide with Elastic Modulus Similar to Soft Tissue
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|c 2024
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|a Text
|b txt
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Revised 17.09.2024
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|a published: Electronic-eCollection
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|a Citation Status PubMed-not-MEDLINE
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|a © 2024 The Authors. Published by American Chemical Society.
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|a Nanometer-scale control over surface functionalization of soft gels is important for a variety of applications including controlling interactions with cells for in vitro cell culture and for regenerative medicine. Recently, we have shown that it is possible to transfer a nanometer-thick precision functional polymer layer to the surface of relatively stiff polyacrylamide gels. Here, we develop a fundamental understanding of the way in which the precision polymer backbone participates in the polyacrylamide radical polymerization and cross-linking process, which enables us to generate high-efficiency transfer to much softer hydrogels (down to 5 kPa) with stiffness similar to that of soft tissue. This approach creates hydrogel surfaces with exposed nanostructured functional arrays that open the door to controlled ligand presentation on soft hydrogel surfaces
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|a Journal Article
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|a Singh, Anamika
|e verfasserin
|4 aut
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1 |
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|a Arango, Juan C
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Claridge, Shelley A
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Chemistry of materials : a publication of the American Chemical Society
|d 1998
|g 36(2024), 17 vom: 10. Sept., Seite 8264-8273
|w (DE-627)NLM098194763
|x 0897-4756
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|g volume:36
|g year:2024
|g number:17
|g day:10
|g month:09
|g pages:8264-8273
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|u http://dx.doi.org/10.1021/acs.chemmater.4c01106
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