Systematic synthesis and identification of monolignol pathway metabolites

Bibliographische Detailangaben
Veröffentlicht in:	The New phytologist. - 1979. - 244(2024), 4 vom: 01. Nov., Seite 1143-1167
1. Verfasser:	Kao, Chung-Ting (VerfasserIn)
Weitere Verfasser:	Yang, Fan-Wei, Wu, Meng-Chen, Hung, Tzu-Huan, Hu, Chen-Wei, Chen, Chiu-Hua, Liou, Pin-Chien, Mai, Te-Lun, Chang, Chia-Chih, Lin, Tung-Yi, Chen, Ying-Lan, Lin, Ying-Chung Jimmy, Su, Jung-Chen
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2024
Zugriff auf das übergeordnete Werk:	The New phytologist
Schlagworte:	Journal Article LC‐MS/MS chemical synthesis lignin monolignol biosynthesis woody angiosperms Lignin 9005-53-2

Beschreibung
Zusammenfassung:	© 2024 The Author(s). New Phytologist © 2024 New Phytologist Foundation. Monolignol serves as the building blocks to constitute lignin, the second abundant polymer on Earth. Despite two decades of diligent efforts, complete identification of all metabolites in the currently proposed monolignol biosynthesis pathway has proven elusive. This limitation also hampers their potential application. One of the primary obstacles is the challenge of assembling a collection of all molecules, because many are commercially unavailable or prohibitively costly. In this study, we established systematic pipelines to synthesize all 24 molecules through the conversions between functional groups on a core structure followed by the application to other core structures. We successfully identified all of them in Populus trichocarpa and Eucalyptus grandis, two representative species respectively from malpighiales and myrtales in angiosperms. Knowledge about monolignol metabolite chemosynthesis and identification will form the foundation for future studies
Beschreibung:	Date Completed 17.10.2024 Date Revised 19.09.2025 published: Print-Electronic Citation Status MEDLINE
ISSN:	1469-8137
DOI:	10.1111/nph.20101