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240915s2024 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.4c02127
|2 doi
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|a eng
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|a Jiang, Yujiu
|e verfasserin
|4 aut
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|a Electrochemical Platform Based on the Bi2Te3 Family of Topological Insulators for the Detection of SARS-CoV-2 Pathogenic Factors
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|c 2024
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|a Text
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Revised 14.09.2024
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|a published: Print-Electronic
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|a Citation Status Publisher
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|a Accurate and rapid detection of the causative agent of a disease is of great importance in controlling the spread of the disease. This work developed a biosensor with the Bi2Te3 family of topological insulators for detection of the SARS-CoV-2 virulence factor. The Bi2Te3 family is a three-dimensional topological insulator material with topologically protected surface states; the presence of these surface states facilitates charge transfer between the electrode and electrolyte interface. Compared with the detection performance of Bi2Se3, BiSbTeSe2, and a trivial insulator like Sb2Se3, Bi2Te3 exhibits superior characteristics. A Bi2Te3 electrochemical detection platform is utilized to fabricate a sensor that can detect SARS-CoV-2 DNA, RNA, and antigen for label-free target detection. The concentration range of DNA detection by the biosensor using Bi2Te3 is between 1.0 × 10-15 and 1.0 × 10-10 M, and the detection limit can reach 1.41 × 10-16 M. Furthermore, it exhibits excellent selectivity and maintains good stability even after being stored for 14 days. This study provides a new way to apply topological insulator materials in the field of biosensors and use their unique electronic structure to improve the accuracy and speed of disease detection and diagnosis
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|a Journal Article
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|a Zhu, Peng
|e verfasserin
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|a Bai, Jiangyue
|e verfasserin
|4 aut
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|a Wang, Zihang
|e verfasserin
|4 aut
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|a Li, Xiuxia
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|a Xu, Shiqi
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|a Zhang, Chunpan
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|a Li, Shanshan
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|a Song, Tinglu
|e verfasserin
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|a Tan, Fan
|e verfasserin
|4 aut
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|a Wang, Zhiwei
|e verfasserin
|4 aut
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| 700 |
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|a Luo, Aiqin
|e verfasserin
|4 aut
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| 700 |
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|a Xie, Bingteng
|e verfasserin
|4 aut
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|a Yang, Yanbo
|e verfasserin
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|a Han, Junfeng
|e verfasserin
|4 aut
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
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|g (2024) vom: 14. Sept.
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|u http://dx.doi.org/10.1021/acs.langmuir.4c02127
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