PRL1 interacts with and stabilizes RPA2A to regulate carbon deprivation-induced senescence in Arabidopsis

© 2024 The Author(s). New Phytologist © 2024 New Phytologist Foundation.

Bibliographische Detailangaben
Veröffentlicht in:The New phytologist. - 1979. - 244(2024), 3 vom: 21. Okt., Seite 855-869
1. Verfasser: Meng, Jingjing (VerfasserIn)
Weitere Verfasser: Zhou, Wenhui, Mao, Xinhao, Lei, Pei, An, Xue, Xue, Hui, Qi, Yafei, Yu, Fei, Liu, Xiayan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:The New phytologist
Schlagworte:Journal Article Arabidopsis NTC PRL1 RPA2A Replication Protein A carbon deprivation stress‐induced senescence Arabidopsis Proteins Carbon mehr... 7440-44-0 PRL1 protein, Arabidopsis ROR1 protein, Arabidopsis
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520 |a Leaf senescence is a developmental program regulated by both endogenous and environmental cues. Abiotic stresses such as nutrient deprivation can induce premature leaf senescence, which profoundly impacts plant growth and crop yield. However, the molecular mechanisms underlying stress-induced senescence are not fully understood. In this work, employing a carbon deprivation (C-deprivation)-induced senescence assay in Arabidopsis seedlings, we identified PLEIOTROPIC REGULATORY LOCUS 1 (PRL1), a component of the NineTeen Complex, as a negative regulator of C-deprivation-induced senescence. Furthermore, we demonstrated that PRL1 directly interacts with the RPA2A subunit of the single-stranded DNA-binding Replication Protein A (RPA) complex. Consistently, the loss of RPA2A leads to premature senescence, while increased expression of RPA2A inhibits senescence. Moreover, overexpression of RPA2A reverses the accelerated senescence in prl1 mutants, and the interaction with PRL1 stabilizes RPA2A under C-deprivation. In summary, our findings reveal the involvement of the PRL1-RPA2A functional module in C-deprivation-induced plant senescence 
650 4 |a Journal Article 
650 4 |a Arabidopsis 
650 4 |a NTC 
650 4 |a PRL1 
650 4 |a RPA2A 
650 4 |a Replication Protein A 
650 4 |a carbon deprivation 
650 4 |a stress‐induced senescence 
650 7 |a Arabidopsis Proteins  |2 NLM 
650 7 |a Carbon  |2 NLM 
650 7 |a 7440-44-0  |2 NLM 
650 7 |a Replication Protein A  |2 NLM 
650 7 |a PRL1 protein, Arabidopsis  |2 NLM 
650 7 |a ROR1 protein, Arabidopsis  |2 NLM 
700 1 |a Zhou, Wenhui  |e verfasserin  |4 aut 
700 1 |a Mao, Xinhao  |e verfasserin  |4 aut 
700 1 |a Lei, Pei  |e verfasserin  |4 aut 
700 1 |a An, Xue  |e verfasserin  |4 aut 
700 1 |a Xue, Hui  |e verfasserin  |4 aut 
700 1 |a Qi, Yafei  |e verfasserin  |4 aut 
700 1 |a Yu, Fei  |e verfasserin  |4 aut 
700 1 |a Liu, Xiayan  |e verfasserin  |4 aut 
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773 1 8 |g volume:244  |g year:2024  |g number:3  |g day:21  |g month:10  |g pages:855-869 
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