The Role of Endoplasmic Reticulum Stress on Reducing Recombinant Protein Production in Mammalian Cells

Therapeutic recombinant protein production relies on industrial scale culture of mammalian cells to produce active proteins in quantities sufficient for clinical use. The combination of stresses from industrial cell culture environment and recombinant protein production can overwhelm the protein syn...

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Bibliographische Detailangaben

Veröffentlicht in:	Biochemical engineering journal. - 1998. - 210(2024) vom: 26. Sept.
1. Verfasser:	Splichal, R Chauncey (VerfasserIn)
Weitere Verfasser:	Chen, Kevin, Walton, S Patrick, Chan, Christina
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2024
Zugriff auf das übergeordnete Werk:	Biochemical engineering journal
Schlagworte:	Journal Article DNA Damage Response Endoplasmic reticulum stress Industrial Cell Culture Protein Production Secretion