Evaluation of the efficiency of various methods to load fluoroquinolones into Escherichia coli outer membrane vesicles as a novel antibiotic delivery platform

The development of novel antibacterial agents that are effective against Gram-negative bacteria is limited primarily by transport issues. This class of bacteria maintains a complex cell envelope consisting of two membrane bilayers, preventing the passage of most antibiotics. These drugs must therefo...

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Bibliographische Detailangaben
Veröffentlicht in:Biochemical engineering journal. - 1998. - 210(2024) vom: 24. Aug.
1. Verfasser: Wu, Meishan (VerfasserIn)
Weitere Verfasser: Holgado, Lauryn, Harrower, Rachael M, Brown, Angela C
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Biochemical engineering journal
Schlagworte:Journal Article Gram-negative bacteria Outer membrane vesicles antibiotic resistance fluoroquinolones