Dynamics of antimicrobial resistance and susceptibility profile in full-scale hospital wastewater treatment plants

© 2024 The Authors This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (CC BY 4.0), which permits copying, adaptation and redistribution, provided the original work is properly cited (http://creativecommons.org/licenses/by/4.0/).

Bibliographische Detailangaben
Veröffentlicht in:Water science and technology : a journal of the International Association on Water Pollution Research. - 1986. - 90(2024), 1 vom: 15. Juli, Seite 103-123
1. Verfasser: Esmaeili-Khoshmardan, Maedeh (VerfasserIn)
Weitere Verfasser: Dabiri, Hossein, Rafiee, Mohammad, Eslami, Akbar, Yazdanbakhsh, Ahmadreza, Amereh, Fatemeh, Jahangiri-Rad, Mahsa, Hashemi, Ali
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Water science and technology : a journal of the International Association on Water Pollution Research
Schlagworte:Journal Article antibiotic-resistant bacteria antibiotic-resistant genes effluent quality parameters hospital wastewater treatment plant resistance profile Wastewater Anti-Bacterial Agents
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520 |a © 2024 The Authors This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (CC BY 4.0), which permits copying, adaptation and redistribution, provided the original work is properly cited (http://creativecommons.org/licenses/by/4.0/). 
520 |a Drug resistance has become a matter of great concern, with many bacteria now resist multiple antibiotics. This study depicts the occurrence of antibiotic-resistant bacteria (ARB) and resistance patterns in five full-scale hospital wastewater treatment plants (WWTPs). Samples of raw influent wastewater, as well as pre- and post-disinfected effluents, were monitored for targeted ARB and resistance genes in September 2022 and February 2023. Shifts in resistance profiles of Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii antimicrobial-resistant indicators in the treated effluent compared to that in the raw wastewater were also worked out. Ceftazidime (6.78 × 105 CFU/mL) and cefotaxime (6.14 × 105 CFU/mL) resistant species showed the highest concentrations followed by ciprofloxacin (6.29 × 104 CFU/mL), and gentamicin (4.88 × 104 CFU/mL), in raw influent respectively. WWTP-D employing a combination of biological treatment and coagulation/clarification for wastewater decontamination showed promising results for reducing ARB emissions from wastewater. Relationships between treated effluent quality parameters and ARB loadings showed that high BOD5 and nitrate levels were possibly contributing to the persistence and/or selection of ARBs in WWTPs. Furthermore, antimicrobial susceptibility tests of targeted species revealed dynamic shifts in resistance profiles through treatment processes, highlighting the potential for ARB and ARGs in hospital wastewater to persist or amplify during treatment 
650 4 |a Journal Article 
650 4 |a antibiotic-resistant bacteria 
650 4 |a antibiotic-resistant genes 
650 4 |a effluent quality parameters 
650 4 |a hospital wastewater treatment plant 
650 4 |a resistance profile 
650 7 |a Wastewater  |2 NLM 
650 7 |a Anti-Bacterial Agents  |2 NLM 
700 1 |a Dabiri, Hossein  |e verfasserin  |4 aut 
700 1 |a Rafiee, Mohammad  |e verfasserin  |4 aut 
700 1 |a Eslami, Akbar  |e verfasserin  |4 aut 
700 1 |a Yazdanbakhsh, Ahmadreza  |e verfasserin  |4 aut 
700 1 |a Amereh, Fatemeh  |e verfasserin  |4 aut 
700 1 |a Jahangiri-Rad, Mahsa  |e verfasserin  |4 aut 
700 1 |a Hashemi, Ali  |e verfasserin  |4 aut 
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