Three Cases of Bilateral Metachronous Testicular Tumors

We present three cases of bilateral metachronous testicular tumors. The patient in case 1 had a history of left orchiectomy for undescended testis at the age of 19. The pathological findings revealed germ cell neoplasia in situ. Twenty-four years later (age=43), he was diagnosed with right testicula...

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Veröffentlicht in:Hinyokika kiyo. Acta urologica Japonica. - 1962. - 70(2024), 3 vom: 15. März, Seite 77-80
1. Verfasser: Takagi, Haruka (VerfasserIn)
Weitere Verfasser: Hori, Jun-Ichi, Morishita, Shun, Makino, Shogo, Otani, Miyu, Kobayashi, Shin, Wada, Naoki, Kitta, Takeya, Kakizaki, Hidehiro
Format: Online-Aufsatz
Sprache:Japanese
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Hinyokika kiyo. Acta urologica Japonica
Schlagworte:Journal Article Case Reports
Beschreibung
Zusammenfassung:We present three cases of bilateral metachronous testicular tumors. The patient in case 1 had a history of left orchiectomy for undescended testis at the age of 19. The pathological findings revealed germ cell neoplasia in situ. Twenty-four years later (age=43), he was diagnosed with right testicular tumor with lymph node and lung metastasis (stage IIIc). Right orchiectomy was performed, and the pathological finding showed nonseminomatous germ cell tumor. He underwent chemotherapy, followed by lymph node dissection and lung metastasectomy. The patient in case 2 had a history of left orchiectomy for testicular tumor at the age of 41. The pathological finding of the left testis revealed seminoma (stage IA). Nineteen years later (age=60), he was diagnosed with right testicular tumor and underwent right orchiectomy. Herein, the pathological finding showed seminoma (stage IA). The patient in case 3 had a history of right orchiectomy for testicular tumor at the age of 25. The pathological findings revealed seminoma (stage IS), and he underwent adjuvant radiation of the para-aortic field without subsequent recurrence. Fourteen years later (age=39), he was diagnosed with left testicular tumor and underwent left orchiectomy. The pathological finding revealed seminoma (stage IB). The patient underwent adjuvant carboplatin monotherapy to prevent recurrence. Due to the long interval between the occurrence of bilateral metachronous testicular tumors (mean=19 years ; three cases), long-term observation is necessary to detect the possible occurrence of contralateral testicular tumors. Contralateral testicular biopsy might be considered at the time of orchiectomy for unilateral testicular tumor if associated with testicular atrophy and/or a history of undescended testis
Beschreibung:Date Completed 04.07.2024
Date Revised 16.10.2024
published: Print
Citation Status MEDLINE
ISSN:0018-1994
DOI:10.14989/ActaUrolJap_70_3_77