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240604s2024 xx |||||o 00| ||eng c |
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|a 10.1007/s10646-024-02763-x
|2 doi
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|a pubmed24n1515.xml
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|a (DE-627)NLM373194455
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|a (NLM)38831228
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Sharma, Darshana
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Lambda-Cyhalothrin induced behavioural, neurotoxic and oxidative stress on vertebrate model Danio rerio (Hamilton-Buchanan 1822)
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| 264 |
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|c 2024
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 28.08.2024
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|a Date Revised 28.08.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
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|a λ-cyhalothrin, a synthetic type II pyrethroid, has become increasingly popular for control of aphids, butterfly larvae, and beetles, replacing other agricultural chemicals. As a result of which, residues of this synthetic pesticide are being reported across the globe in natural water, which poses a serious threat to aquatic life. Therefore, the present study was designed to understand the toxicity effects of λ-cyhalothrin on behaviour, oxidative stress and neurotoxicity in a vertebrate aquatic model, zebrafish (Danio rerio). The fish were exposed to 0.129, 0.194 and 0.388 µg/L corresponding to 5%, 10% and 20% of 96hLC50 (1.94 µg/L) for 28 days. Upon exposure to the highest concentration (0.388 µg/L), the test animal exhibited significant alterations in behavioural patterns like number of entries to the top zone (n), decrease in average speed (m/s) and decrease in time spent in top zone (s). Moreover, the shoaling test demonstrated a significant decrease (p < 0.05) in the relative time spent by the tested fish (%) near the stimulus fish. The change in behavioural alterations might be linked to a significant decrease (p < 0.05) in the brain acetylcholine esterase activity. Furthermore, the present study also illustrates oxidative stress exerted by λ-cyhalothrin through an increase in the production of reactive oxygen species, which is again clearly depicted by a significant increase (p < 0.05) in Superoxide dismutase, Catalase and Glutathione peroxidase activities. Overall, the present study systematically demonstrates the chronic effects of λ-cyhalothrin on adult fish behaviour and physiology, which will contribute to assessing the risks of λ-cyhalothrin to organismal health
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|a Journal Article
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|a Antioxidant enzymes
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| 650 |
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|a Behaviour
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| 650 |
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4 |
|a Neurotoxicology
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| 650 |
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4 |
|a Pyrethroids
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| 650 |
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|a Zebrafish
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| 650 |
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|a λ-cyhalothrin
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| 650 |
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|a Pyrethrins
|2 NLM
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| 650 |
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7 |
|a Nitriles
|2 NLM
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| 650 |
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|a cyhalothrin
|2 NLM
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| 650 |
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7 |
|a V0V73PEB8M
|2 NLM
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| 650 |
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7 |
|a Water Pollutants, Chemical
|2 NLM
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| 650 |
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7 |
|a Insecticides
|2 NLM
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| 700 |
1 |
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|a Sarmah, Raktim
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Sarmah, Rimon
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Pokhrel, Hemanta
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Bhagabati, Sarada Kanta
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Sarma, Dipak Kumar
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Patowary, Arnab Narayan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Mili, Karishma
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Ecotoxicology (London, England)
|d 1992
|g 33(2024), 7 vom: 01. Aug., Seite 663-676
|w (DE-627)NLM098212214
|x 1573-3017
|7 nnns
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| 773 |
1 |
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|g volume:33
|g year:2024
|g number:7
|g day:01
|g month:08
|g pages:663-676
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|u http://dx.doi.org/10.1007/s10646-024-02763-x
|3 Volltext
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