|
|
|
|
| LEADER |
01000caa a22002652 4500 |
| 001 |
NLM372599877 |
| 003 |
DE-627 |
| 005 |
20240530232953.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
240521s2024 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1002/adma.202403813
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1423.xml
|
| 035 |
|
|
|a (DE-627)NLM372599877
|
| 035 |
|
|
|a (NLM)38771625
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Fonseca, Javier
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Metal-Organic Framework-Based Antimicrobial Touch Surfaces to Prevent Cross-Contamination
|
| 264 |
|
1 |
|c 2024
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Revised 30.05.2024
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status Publisher
|
| 520 |
|
|
|a © 2024 The Author(s). Advanced Materials published by Wiley‐VCH GmbH.
|
| 520 |
|
|
|a Infection diseases are a major threat to global public health, with nosocomial infections being of particular concern. In this context, antimicrobial coatings emerge as a promising prophylactic strategy to reduce the transmission of pathogens and control infections. Here, antimicrobial door handle covers to prevent cross-contamination are prepared by incorporating iodine-loaded UiO-66 microparticles into a potentially biodegradable polyurethane polymer (Baycusan eco E 1000). These covers incorporate MOF particles that serve as both storage reservoirs and delivery systems for the biocidal iodine. Under realistic touching conditions, the door handle covers completely inhibit the transmission of Gram-positive bacterial species (Staphylococcus aureus, and Enterococcus faecalis), Gram-negative bacterial species (Escherichia coli, Pseudomonas aeruginosa, and Acinetobacter baumannii), and fungi (Candida albicans). The covers remain effective even after undergoing multiple contamination cycles, after being cleaned, and when tinted to improve discretion and usability. Furthermore, as the release of iodine from the door handle covers follow hindered Fickian diffusion, their antimicrobial lifetime is calculated to be as long as approximately two years. Together, these results demonstrate the potential of these antimicrobial door handle covers to prevent cross-contamination, and underline the efficacy of integrating MOFs into innovative technologies
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a antimicrobial coatings
|
| 650 |
|
4 |
|a delivery systems
|
| 650 |
|
4 |
|a iodine
|
| 650 |
|
4 |
|a metal–organic frameworks (MOFs)
|
| 650 |
|
4 |
|a prototypes
|
| 700 |
1 |
|
|a Cano-Sarabia, Mary
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Cortés, Pilar
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Saldo, Jordi
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Montpeyó, David
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Lorenzo, Julia
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Llagostera, Montserrat
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Imaz, Inhar
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Maspoch, Daniel
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g (2024) vom: 21. Mai, Seite e2403813
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
|
| 773 |
1 |
8 |
|g year:2024
|g day:21
|g month:05
|g pages:e2403813
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1002/adma.202403813
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|j 2024
|b 21
|c 05
|h e2403813
|