Budding mutation reprogrammed flavonoid biosynthesis in jujube by deploying MYB41 and bHLH93

Published by Elsevier Masson SAS.

Bibliographische Detailangaben
Veröffentlicht in:Plant physiology and biochemistry : PPB. - 1991. - 211(2024) vom: 11. Juni, Seite 108665
1. Verfasser: Jin, Juan (VerfasserIn)
Weitere Verfasser: Li, Lili, Fan, Dingyu, Du, Youwei, Jia, Hongchen, Yang, Lei, Jia, Wensuo, Hao, Qing
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Plant physiology and biochemistry : PPB
Schlagworte:Journal Article Budding mutation Flavonoids Jujube MYB41 Muti-omics bHLH93 Plant Proteins Basic Helix-Loop-Helix Transcription Factors Transcription Factors
Beschreibung
Zusammenfassung:Published by Elsevier Masson SAS.
Budding mutations are known to cause metabolic changes in new jujube varieties; however, the mechanisms underlying these changes are still unclear. Here, we performed muti-omics analysis to decipher the detailed metabolic landscape of "Saimisu 1" (S1) and its budding mutation line "Saimisu 2" (S2) at all fruit stages. We found that the genes involved in the biosyntheses of flavonoids, phenylpropanoids, and amino acids were upregulated in S2 fruits at all stages, especially PAL and DFR, resulting in increased accumulation of related compounds in S2 mature fruits. Further co-expression regulatory network analysis showed that the transcription factors MYB41 and bHLH93 potentially regulated the expression of PAL and DFR, respectively, by directly binding to their promoters. Moreover, the overexpression of MYB41 or bHLH93 induced their expression levels to redirect the flux of the flavonoid biosynthetic pathway, eventually leading to high levels of related compounds in S2 fruits. Overall, this study revealed the metabolic variations between S1 and S2 and contributed to the understanding of the mechanisms underlying budding mutation-mediated metabolic variations in plants, eventually providing the basis for breeding excellent jujube varieties using budding mutation lines
Beschreibung:Date Completed 24.05.2024
Date Revised 08.06.2024
published: Print-Electronic
Citation Status MEDLINE
ISSN:1873-2690
DOI:10.1016/j.plaphy.2024.108665