Original Article--Clinical and Procedural Characteristics of Successful Transcatheter Device Closure of Ostium Secundum Atrial Septal Defect in Symptomatic Children Weighing <15 kg : A Retrospective Study Spanning One Decade From South India

© 2024 Saudi Heart Association.

Bibliographische Detailangaben
Veröffentlicht in:Journal of the Saudi Heart Association. - 1999. - 36(2024), 1 vom: 30., Seite 14-22
1. Verfasser: Joseph, Shobhit P (VerfasserIn)
Weitere Verfasser: Mirza, Shohiab U R, Krupa, Jesu, Varghese, Shruti I, Kartha, Gayathri B, George, Oommen K, George, Paul V, Jose, John, Thomson, Viji S
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Journal of the Saudi Heart Association
Schlagworte:Journal Article Atrial septal defect Small children Transcatheter device closure
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245 1 0 |a Original Article--Clinical and Procedural Characteristics of Successful Transcatheter Device Closure of Ostium Secundum Atrial Septal Defect in Symptomatic Children Weighing <15 kg  |b A Retrospective Study Spanning One Decade From South India 
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520 |a © 2024 Saudi Heart Association. 
520 |a Objectives: This retrospective study sought to determine the feasibility of transcatheter atrial septal defect device closure in patients less than 15 kg, as well as to assess complication rates and the reasons for unsuccessful device closure 
520 |a Background: In general, the risks associated with transcatheter atrial septal defect device closure are believed and reported to be relatively low, but the evidence stems from trials involving adults and older children. Current guidelines do not recommend atrial defect closure in device closure in children <15 kg, due to limited data available for feasibility and safety of device closure in this group of patients 
520 |a Methods: Retrospective review of all patients who underwent elective transcatheter closure of ostium secundum atrial septal defect between September 2013 to February 2022. We excluded all children above 15 kg, as well as those with complex congenital heart defects. Major and minor complications were predefined and indications for referral were evaluated 
520 |a Results: We identified 81 patients meeting criteria with a median procedural age of 3 years (1 year-8 years), and median weight of 12 kg (4-15 kg). Successful device closure was achieved in 95.1% (77/81) and in 4.9% (4/81), the procedure was aborted. There was 1 major (1.2%) and 1 minor (1.2%) complication, total complication rate (2.4%). 100% of the referrals had right heart enlargement and exertional dyspnoea, 18.5% had recurrent lower respiratory tract infection and 9.9% had failure to thrive. Rate of resolution of residual shunt was 95.1%. at post-procedure day 1 and 98.8% at post-procedure 3 and 6 months respectively 
520 |a Conclusions: Percutaneous atrial septal defect closure can be done effectively and safely in symptomatic children weighing less than 15 kg in experienced centres. However, deferral for closure until the historically established timeline of around 4-5 years of age should be strongly considered in asymptomatic children 
650 4 |a Journal Article 
650 4 |a Atrial septal defect 
650 4 |a Small children 
650 4 |a Transcatheter device closure 
700 1 |a Mirza, Shohiab U R  |e verfasserin  |4 aut 
700 1 |a Krupa, Jesu  |e verfasserin  |4 aut 
700 1 |a Varghese, Shruti I  |e verfasserin  |4 aut 
700 1 |a Kartha, Gayathri B  |e verfasserin  |4 aut 
700 1 |a George, Oommen K  |e verfasserin  |4 aut 
700 1 |a George, Paul V  |e verfasserin  |4 aut 
700 1 |a Jose, John  |e verfasserin  |4 aut 
700 1 |a Thomson, Viji S  |e verfasserin  |4 aut 
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