Case Report : Macula Structural and Functional Assessment in Nab-Paclitaxel-Related Cystoid Macular Edema

Nab-paclitaxel-related cystoid macular edema is a rare ophthalmic adverse drug reaction. We present a 54-year-old woman with metastatic hormone receptor positive, HER-2 negative breast carcinoma who developed profound bilateral vision loss after the seventh cycle of nab-paclitaxel treatment. Optical...

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Veröffentlicht in:Ophthalmic surgery, lasers & imaging retina. - 2013. - 55(2024), 7 vom: 26. Juli, Seite 408-411
1. Verfasser: Kwok, Lawrence (VerfasserIn)
Weitere Verfasser: Mahmood, Alina, Kumar, Sanjeev, Chang, Andrew
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Ophthalmic surgery, lasers & imaging retina
Schlagworte:Case Reports Journal Article Paclitaxel P88XT4IS4D 130-nm albumin-bound paclitaxel Albumins Antineoplastic Agents, Phytogenic
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520 |a Nab-paclitaxel-related cystoid macular edema is a rare ophthalmic adverse drug reaction. We present a 54-year-old woman with metastatic hormone receptor positive, HER-2 negative breast carcinoma who developed profound bilateral vision loss after the seventh cycle of nab-paclitaxel treatment. Optical coherence tomography and macula microperimetry demonstrated macular edema and decreased threshold sensitivity, respectively. Cessation of nab-paclitaxel improved structural and functional vision after 4 weeks. The introduction of topical dorzolamide 1% in one eye demonstrated further rapid resolution of edema. We demonstrate the objective and subjective visual changes and recovery of nab-paclitaxel-related cystoid macular edema. [Ophthalmic Surg Lasers Imaging Retina 2024;55:408-411.] 
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