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240325s2024 xx |||||o 00| ||eng c |
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|a 10.1111/jfd.13940
|2 doi
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|a pubmed24n1436.xml
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|a (NLM)38523352
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|e rakwb
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|a eng
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|a Abu Aziz, Nurhikmah
|e verfasserin
|4 aut
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| 245 |
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|a Comparative proteome analysis revealed potential biomarkers and the underlying immune mechanisms in Vibrio-resistant hybrid grouper, Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂
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|c 2024
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 07.06.2024
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|a Date Revised 07.06.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2024 John Wiley & Sons Ltd.
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|a Vibrio alginolyticus is the causative agent of vibriosis, a common bacterial infection in grouper aquaculture that is associated with the development of haemorrhagic and non-haemorrhagic ulcerations on the fish. In the present study, comparative proteome analysis was performed on serum samples from Vibrio-resistant and Vibrio-susceptible grouper. Samples were analysed using high-throughput LC-MS/MS and identified 2770 unique peptides that corresponded to 344 proteins. Subsequent analysis identified 21 proteins that were significantly up-regulated in the resistant group compared to the control and the susceptible groups. Those proteins are associated with immunostimulatory effects, signalling and binding cascade, metabolism, and maintaining tissue integrity and physiological condition. Besides, potential protein biomarkers related to the immune system were identified, which could be associated with the disease-resistant phenotype. These data provide insights into the underlying immune mechanism of hybrid groupers upon Vibrio sp. infection
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|a Journal Article
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|a Vibrio alginolyticus
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| 650 |
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4 |
|a disease‐resistant phenotype
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| 650 |
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4 |
|a hybrid grouper
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| 650 |
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4 |
|a serum proteome
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| 650 |
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4 |
|a vibriosis
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| 650 |
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7 |
|a Proteome
|2 NLM
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| 650 |
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7 |
|a Biomarkers
|2 NLM
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| 650 |
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7 |
|a Fish Proteins
|2 NLM
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| 700 |
1 |
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|a Christianus, Annie
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wan Solahudin, Wan Mohd Syazwan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ismail, Intan Safinar
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Low, Chen-Fei
|e verfasserin
|4 aut
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| 773 |
0 |
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|i Enthalten in
|t Journal of fish diseases
|d 1998
|g 47(2024), 7 vom: 01. Juni, Seite e13940
|w (DE-627)NLM098166034
|x 1365-2761
|7 nnns
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| 773 |
1 |
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|g volume:47
|g year:2024
|g number:7
|g day:01
|g month:06
|g pages:e13940
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| 856 |
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|u http://dx.doi.org/10.1111/jfd.13940
|3 Volltext
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