Prevalence of amyloid deposition and cardiac amyloidosis in shoulder disease compared to carpal tunnel syndrome

© 2023 The Authors.

Bibliographische Detailangaben
Veröffentlicht in:JSES international. - 2020. - 8(2024), 2 vom: 15. März, Seite 349-354
1. Verfasser: Yamada, Eriku (VerfasserIn)
Weitere Verfasser: Umemoto, Tomoyuki, Taguchi, Towako, Onishi, Iichiroh, Yamamoto, Akiko, Tsukamoto, Kazuya, Ibara, Takuya, Sasaki, Toru, Kaburagi, Hidetoshi, Maejima, Yasuhiro, Sasano, Tetsuo, Ohashi, Kenichi, Yoshii, Toshitaka, Nimura, Akimoto, Fujita, Koji
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:JSES international
Schlagworte:Journal Article Amyloid Biceps brachii Cardiac amyloidosis Carpal tunnel syndrome Rotator cuff tear Shoulder disease Shoulder surgery
LEADER 01000caa a22002652 4500
001 NLM369541677
003 DE-627
005 20240312234348.0
007 cr uuu---uuuuu
008 240311s2024 xx |||||o 00| ||eng c
024 7 |a 10.1016/j.jseint.2023.11.009  |2 doi 
028 5 2 |a pubmed24n1324.xml 
035 |a (DE-627)NLM369541677 
035 |a (NLM)38464439 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Yamada, Eriku  |e verfasserin  |4 aut 
245 1 0 |a Prevalence of amyloid deposition and cardiac amyloidosis in shoulder disease compared to carpal tunnel syndrome 
264 1 |c 2024 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Revised 12.03.2024 
500 |a published: Electronic-eCollection 
500 |a Citation Status PubMed-not-MEDLINE 
520 |a © 2023 The Authors. 
520 |a Background: Cardiac amyloidosis is a fatal disease of severe heart failure caused by the accumulation of amyloid in the myocardium. This disease is often advanced by the time cardiac symptoms appear; therefore, early detection and treatment are critical for a good prognosis. Recently, it has been suggested that cardiac amyloidosis is implicated in several orthopedic diseases, including carpal tunnel syndrome (CTS), which is often reported to precede cardiac dysfunction. Shoulder disease has also been suggested to be associated with cardiac amyloidosis; however, there have been no reports investigating the rate of amyloid deposition in shoulder specimens and the simultaneous prevalence of cardiac amyloidosis. Herein, we investigated the prevalence of intraoperative specimen amyloid deposition and cardiac amyloidosis in shoulder disease and CTS to determine the usefulness of shoulder specimen screening as a predictor of cardiac amyloidosis development 
520 |a Methods: A total of 41 patients undergoing arthroscopic shoulder surgery and 33 patients undergoing CTS surgery were enrolled in this study. The shoulder group included rotator cuff tears, contracture of the shoulder, synovitis, and calcific tendonitis. In the shoulder group, a small sample of synovium and the long head of the biceps brachii tendon were harvested, while the transverse carpal ligament was harvested from the CTS group. The intraoperative specimens were pathologically examined for amyloid deposition, and patients with amyloid deposition were examined for the presence of cardiac amyloidosis by cardiac evaluation 
520 |a Results: In the shoulder group, three cases (7.3%) of transthyretin amyloid deposition were found, all of which involved rotator cuff tears. None of these three cases with amyloid deposition were associated with cardiac amyloidosis. When examining the specimens, the amyloid deposition rate in the long head of the biceps brachii tendon was higher than that in the synovium. In the CTS group, 12 cases (36.4%) of transthyretin amyloid deposition were observed. Of these cases, seven underwent cardiac evaluation and two were identified with cardiac amyloidosis 
520 |a Conclusion: While the prevalence of amyloid deposition and cardiac amyloidosis in the CTS group was consistent with previous reports, the shoulder group showed a lower deposition rate and no concomitant cardiac amyloidosis. Therefore, it remains debatable whether investigating amyloid deposition in samples obtained from shoulder surgery is beneficial for the early detection of cardiac amyloidosis 
650 4 |a Journal Article 
650 4 |a Amyloid 
650 4 |a Biceps brachii 
650 4 |a Cardiac amyloidosis 
650 4 |a Carpal tunnel syndrome 
650 4 |a Rotator cuff tear 
650 4 |a Shoulder disease 
650 4 |a Shoulder surgery 
700 1 |a Umemoto, Tomoyuki  |e verfasserin  |4 aut 
700 1 |a Taguchi, Towako  |e verfasserin  |4 aut 
700 1 |a Onishi, Iichiroh  |e verfasserin  |4 aut 
700 1 |a Yamamoto, Akiko  |e verfasserin  |4 aut 
700 1 |a Tsukamoto, Kazuya  |e verfasserin  |4 aut 
700 1 |a Ibara, Takuya  |e verfasserin  |4 aut 
700 1 |a Sasaki, Toru  |e verfasserin  |4 aut 
700 1 |a Kaburagi, Hidetoshi  |e verfasserin  |4 aut 
700 1 |a Maejima, Yasuhiro  |e verfasserin  |4 aut 
700 1 |a Sasano, Tetsuo  |e verfasserin  |4 aut 
700 1 |a Ohashi, Kenichi  |e verfasserin  |4 aut 
700 1 |a Yoshii, Toshitaka  |e verfasserin  |4 aut 
700 1 |a Nimura, Akimoto  |e verfasserin  |4 aut 
700 1 |a Fujita, Koji  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t JSES international  |d 2020  |g 8(2024), 2 vom: 15. März, Seite 349-354  |w (DE-627)NLM307818438  |x 2666-6383  |7 nnns 
773 1 8 |g volume:8  |g year:2024  |g number:2  |g day:15  |g month:03  |g pages:349-354 
856 4 0 |u http://dx.doi.org/10.1016/j.jseint.2023.11.009  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_50 
912 |a GBV_ILN_65 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 8  |j 2024  |e 2  |b 15  |c 03  |h 349-354