Structuring and Shaping of Mechanically Robust and Functional Hydrogels toward Wearable and Implantable Applications

© 2024 Wiley‐VCH GmbH.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 36(2024), 23 vom: 28. Juni, Seite e2309952
1. Verfasser: Wang, Xiao-Qiao (VerfasserIn)
Weitere Verfasser: Xie, An-Quan, Cao, Pengle, Yang, Jian, Ong, Wei Li, Zhang, Ke-Qin, Ho, Ghim Wei
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2024
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Review bioelectronics biomedical mechanical functions shaping soft robots tough hydrogels Hydrogels Biocompatible Materials Polymers
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520 |a Hydrogels possess unique features such as softness, wetness, responsiveness, and biocompatibility, making them highly suitable for biointegrated applications that have close interactions with living organisms. However, conventional man-made hydrogels are usually soft and brittle, making them inferior to the mechanically robust biological hydrogels. To ensure reliable and durable operation of biointegrated wearable and implantable devices, mechanical matching and shape adaptivity of hydrogels to tissues and organs are essential. Recent advances in polymer science and processing technologies have enabled mechanical engineering and shaping of hydrogels for various biointegrated applications. In this review, polymer network structuring strategies at micro/nanoscales for toughening hydrogels are summarized, and representative mechanical functionalities that exist in biological materials but are not easily achieved in synthetic hydrogels are further discussed. Three categories of processing technologies, namely, 3D printing, spinning, and coating for fabrication of tough hydrogel constructs with complex shapes are reviewed, and the corresponding hydrogel toughening strategies are also highlighted. These developments enable adaptive fabrication of mechanically robust and functional hydrogel devices, and promote application of hydrogels in the fields of biomedical engineering, bioelectronics, and soft robotics 
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700 1 |a Xie, An-Quan  |e verfasserin  |4 aut 
700 1 |a Cao, Pengle  |e verfasserin  |4 aut 
700 1 |a Yang, Jian  |e verfasserin  |4 aut 
700 1 |a Ong, Wei Li  |e verfasserin  |4 aut 
700 1 |a Zhang, Ke-Qin  |e verfasserin  |4 aut 
700 1 |a Ho, Ghim Wei  |e verfasserin  |4 aut 
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