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240229s2024 xx |||||o 00| ||eng c |
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|a 10.1002/adma.202309952
|2 doi
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|a pubmed24n1443.xml
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|a DE-627
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|e rakwb
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|a eng
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|a Wang, Xiao-Qiao
|e verfasserin
|4 aut
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|a Structuring and Shaping of Mechanically Robust and Functional Hydrogels toward Wearable and Implantable Applications
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|c 2024
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|a Text
|b txt
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 07.06.2024
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|a Date Revised 17.06.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2024 Wiley‐VCH GmbH.
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|a Hydrogels possess unique features such as softness, wetness, responsiveness, and biocompatibility, making them highly suitable for biointegrated applications that have close interactions with living organisms. However, conventional man-made hydrogels are usually soft and brittle, making them inferior to the mechanically robust biological hydrogels. To ensure reliable and durable operation of biointegrated wearable and implantable devices, mechanical matching and shape adaptivity of hydrogels to tissues and organs are essential. Recent advances in polymer science and processing technologies have enabled mechanical engineering and shaping of hydrogels for various biointegrated applications. In this review, polymer network structuring strategies at micro/nanoscales for toughening hydrogels are summarized, and representative mechanical functionalities that exist in biological materials but are not easily achieved in synthetic hydrogels are further discussed. Three categories of processing technologies, namely, 3D printing, spinning, and coating for fabrication of tough hydrogel constructs with complex shapes are reviewed, and the corresponding hydrogel toughening strategies are also highlighted. These developments enable adaptive fabrication of mechanically robust and functional hydrogel devices, and promote application of hydrogels in the fields of biomedical engineering, bioelectronics, and soft robotics
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|a Journal Article
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|a Review
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|a bioelectronics
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|a biomedical
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|a mechanical functions
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|a shaping
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|a soft robots
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|a tough hydrogels
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|a Hydrogels
|2 NLM
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|a Biocompatible Materials
|2 NLM
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|a Polymers
|2 NLM
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1 |
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|a Xie, An-Quan
|e verfasserin
|4 aut
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1 |
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|a Cao, Pengle
|e verfasserin
|4 aut
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1 |
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|a Yang, Jian
|e verfasserin
|4 aut
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1 |
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|a Ong, Wei Li
|e verfasserin
|4 aut
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1 |
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|a Zhang, Ke-Qin
|e verfasserin
|4 aut
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|a Ho, Ghim Wei
|e verfasserin
|4 aut
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
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|g 36(2024), 23 vom: 28. Juni, Seite e2309952
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|u http://dx.doi.org/10.1002/adma.202309952
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