Synthesis of an Indazole/Indazolium Phosphine Ligand Scaffold and Its Application in Gold(I) Catalysis
© 2023 American Chemical Society.
| Veröffentlicht in: | Organometallics. - 1998. - 42(2023), 19 vom: 09. Okt., Seite 2742-2746 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , |
| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2023
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| Zugriff auf das übergeordnete Werk: | Organometallics |
| Schlagworte: | Journal Article |
| Zusammenfassung: | © 2023 American Chemical Society. Advances in ligand development have allowed for the fine-tuning of gold catalysis. To contribute to this field, we designed an indazole phosphine ligand scaffold that allows facile introduction of cationic charge through methylation. With minimal changes to the structure upon methylation, we could assess the importance of the electronic effects of the insertion of a positive charge on the catalytic activity of the resulting gold(I) complex. Using the benchmark reactions of propargyl amide cyclization and enyne cyclization with and without hexafluoroisopropanol (HFIP), we observed marked differences in the catalytic activities of the neutral and cationic gold species |
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| Beschreibung: | Date Revised 16.02.2024 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
| ISSN: | 0276-7333 |
| DOI: | 10.1021/acs.organomet.3c00354 |